{"id":10646,"date":"2021-05-05T16:34:28","date_gmt":"2021-05-05T14:34:28","guid":{"rendered":"https:\/\/natureight.com\/?p=10646"},"modified":"2021-05-05T16:34:28","modified_gmt":"2021-05-05T14:34:28","slug":"laction-du-cbd-sur-la-maladie-dalzheimer","status":"publish","type":"post","link":"https:\/\/natureight.com\/fr\/effets-et-etudes-du-cbd\/laction-du-cbd-sur-la-maladie-dalzheimer\/","title":{"rendered":"L’action du CBD sur la maladie d\u2019Alzheimer"},"content":{"rendered":"

La maladie d\u2019Alzheimer est une maladie neurod\u00e9g\u00e9n\u00e9rative qui touche des millions de personnes dans le monde. Il n\u2019existe actuellement aucun traitement pour en gu\u00e9rir.<\/p>\n

N\u00e9anmoins, de r\u00e9centes \u00e9tudes sur le sujet mettent en avant les bienfaits du CBD \u00e0 haute dose sur cette maladie notamment au stade pr\u00e9coce dans le cas d\u2019une forme h\u00e9r\u00e9ditaire. C\u2019est le cas de l\u2019\u00e9tude am\u00e9ricaine men\u00e9e par le Medical College of Georgia de l\u2019Universit\u00e9 Augusta.<\/p>\n

En quoi le CBD peut \u00eatre utile dans la maladie d\u2019Alzheimer\u00a0?<\/h2>\n

Diff\u00e9rents facteurs peuvent \u00eatre \u00e0 l\u2019origine de la maladie d\u2019Alzheimer\u00a0: l\u2019\u00e2ge, le patrimoine g\u00e9n\u00e9tique, le mode de vie, \u2026<\/p>\n

Les sympt\u00f4mes sont dus \u00e0 des d\u00e9p\u00f4ts de prot\u00e9ines (b\u00eata-amylo\u00efdes) qui s\u2019agr\u00e8gent sous forme de plaques insolubles au niveau du cerveau. Ces d\u00e9p\u00f4ts entra\u00eenent l\u2019asphyxie et la mort progressive des cellules du cerveau. Le traitement de l\u2019information s\u2019en trouve perturb\u00e9, ce qui affecte la m\u00e9moire \u00e0 court puis \u00e0 long terme. On parle de d\u00e9mence.<\/p>\n

La maladie serait associ\u00e9e entre autres \u00e0 l\u2019inflammation des tissus nerveux, appel\u00e9e neuroinflammation. Or selon une \u00e9tude<\/a>, les cannabino\u00efdes poss\u00e8dent des propri\u00e9t\u00e9s neuroprotectrices et pr\u00e9servent les cellules contre l\u2019effet toxique des b\u00eata-amylo\u00efdes.<\/p>\n

Le CBD<\/a> contribuerait donc \u00e0 r\u00e9duire les taux de prot\u00e9ines li\u00e9es \u00e0 l\u2019inflammation chez les patients atteints d\u2019Alzheimer. Le CBD est par ailleurs r\u00e9put\u00e9 pour son action anti-inflammatoire<\/a>.<\/p>\n

Le CBD a une incidence sur l\u2019\u00e9limination des prot\u00e9ines b\u00eata-amylo\u00efdes et sur le taux de prot\u00e9ines li\u00e9es \u00e0 l\u2019inflammation<\/h2>\n

En temps normal, les prot\u00e9ines b\u00eata-amylo\u00efdes ainsi que les autres d\u00e9chets dans le cerveau sont \u00e9limin\u00e9s, notamment gr\u00e2ce aux prot\u00e9ines IL-33 et TREM2. Chez les patients atteints de la maladie d\u2019Alzheimer, les taux de ces deux prot\u00e9ines sont inf\u00e9rieurs \u00e0 la normale. Sans ces prot\u00e9ines, les b\u00eata-amylo\u00efdes s\u2019accumulent et forment ces fameuses plaques qui \u00e9touffent les cellules nerveuses, responsables de la transmission des messages.<\/p>\n

Une r\u00e9cente \u00e9tude<\/a> a permis de mettre en \u00e9vidence, d\u2019un part, l\u2019action b\u00e9n\u00e9fique du CBD \u00e0 forte dose sur ces taux de prot\u00e9ines IL-33 et TREM2, et d\u2019autre part, la r\u00e9duction du taux d\u2019une autre prot\u00e9ine (IL-6), responsable de l\u2019inflammation.<\/p>\n

Toujours dans cette \u00e9tude, les scientifiques ont constat\u00e9, chez les souris, un taux d\u2019IL-33 sept \u00e0 dix fois sup\u00e9rieur au taux avant l\u2019injection de cannabidiol.<\/p>\n

Les travaux sur le sujet n\u2019en sont encore qu\u2019au tout d\u00e9but et des recherches compl\u00e9mentaires sont \u00e0 entreprendre, notamment pour pr\u00e9ciser le dosage, mais aussi pour \u00e9valuer les effets du CBD sur les patients souffrant d\u2019un Alzheimer pr\u00e9coce. L\u2019id\u00e9e de trouver un rem\u00e8de \u00e0 cette maladie, gr\u00e2ce au CBD, est de plus en plus probable.<\/p>\n

D\u2019autres \u00e9tudes sur le sujet<\/h2>\n

D\u2019autres \u00e9tudes viennent corroborer l\u2019utilit\u00e9 du CBD dans la lutte contre la maladie d\u2019Alzheimer.<\/p>\n

Selon l\u2019une d\u2019entre elles, le ciblage de prot\u00e9ines GPR55 pourrait \u00eatre une autre option pour traiter diff\u00e9rentes maladies neurod\u00e9g\u00e9n\u00e9ratives telles que Parkinson, Alzheimer et la scl\u00e9rose en plaques.<\/p>\n

Une autre encore d\u00e9voile que le CBD am\u00e9liore le flux sanguin vers les parties du cerveau associ\u00e9es \u00e0 la m\u00e9moire et la prise de d\u00e9cision. Cela constitue un autre axe de recherche et un nouvel espoir de trouver enfin un rem\u00e8de \u00e0 cette maladie aujourd\u2019hui incurable.<\/p>\n","protected":false},"excerpt":{"rendered":"

La maladie d\u2019Alzheimer est une maladie neurod\u00e9g\u00e9n\u00e9rative qui touche des millions de personnes dans le monde. Il n\u2019existe actuellement aucun traitement pour en gu\u00e9rir. N\u00e9anmoins, de r\u00e9centes \u00e9tudes sur le sujet mettent en avant les bienfaits du CBD \u00e0 haute dose sur cette maladie notamment au stade pr\u00e9coce dans le cas d\u2019une forme h\u00e9r\u00e9ditaire. C\u2019est … <\/p>\n

Lire la suite<\/a><\/p>\n","protected":false},"author":1099,"featured_media":10647,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"generate_page_header":"","mc4wp_mailchimp_campaign":[],"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[214],"tags":[],"class_list":["post-10646","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-effets-et-etudes-du-cbd","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50"],"yoast_head":"\nL'action du CBD sur la maladie d\u2019Alzheimer - NATUREIGHT<\/title>\n<meta name=\"description\" content=\"Pathologie neurod\u00e9g\u00e9n\u00e9rative, la maladie d\u2019Alzheimer pourrait bien \u00eatre trait\u00e9es d\u2019ici quelques ann\u00e9es gr\u00e2ce au CBD, selon les derni\u00e8res \u00e9tudes.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/natureight.com\/fr\/effets-et-etudes-du-cbd\/laction-du-cbd-sur-la-maladie-dalzheimer\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L'action du CBD sur la maladie d\u2019Alzheimer - 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