{"id":10361,"date":"2021-03-24T17:46:41","date_gmt":"2021-03-24T15:46:41","guid":{"rendered":"https:\/\/natureight.com\/?p=10361"},"modified":"2021-03-24T17:46:41","modified_gmt":"2021-03-24T15:46:41","slug":"le-cbd-un-traitement-prometteur-pour-lutter-contre-la-sclerose-en-plaques","status":"publish","type":"post","link":"https:\/\/natureight.com\/fr\/effets-et-etudes-du-cbd\/le-cbd-un-traitement-prometteur-pour-lutter-contre-la-sclerose-en-plaques\/","title":{"rendered":"Le CBD, un traitement prometteur pour lutter contre la scl\u00e9rose en plaques"},"content":{"rendered":"

Aujourd\u2019hui, l\u2019utilisation m\u00e9dicale du cannabis (CBD et THC) pour lutter contre la douleur chronique et la spasticit\u00e9 chez les personnes souffrant de scl\u00e9rose en plaques (ou SEP) est en augmentation. Toutefois, les preuves attestant de la s\u00e9curit\u00e9 de ce traitement \u00e0 base d\u2019huiles de cannabis m\u00e9dical restent encore limit\u00e9es \u00e0 l\u2019heure actuelle.<\/p>\n

Soulager les sympt\u00f4mes de sa scl\u00e9rose en plaques gr\u00e2ce au CBD et au THC<\/h2>\n

Une r\u00e9cente \u00e9tude observationnelle, consultable ici<\/a>, a entrepris d\u2019analyser l\u2019innocuit\u00e9 des huiles de cannabis m\u00e9dical sublinguales aupr\u00e8s des patients atteints par la scl\u00e9rose en plaque.<\/p>\n

Pour mener \u00e0 bien cette \u00e9tude, 28 patients sujets \u00e0 la scl\u00e9rose en plaques ont suivi un traitement \u00e0 base d\u2019huiles de cannabis m\u00e9dical, qui combinaient une forte concentration de CBD et de THC.<\/p>\n

Ils ont ensuite \u00e9t\u00e9 suivis durant une p\u00e9riode d\u2019un mois\u00a0: leur premi\u00e8re \u00e9valuation s\u2019est tenue au d\u00e9but du traitement, et la deuxi\u00e8me \u00e0 l\u2019issue des 4 semaines suivant la prise de ce traitement. Pour chacune de ces visites, les patients se sont pr\u00eat\u00e9s \u00e0 de nombreux examens\u00a0: examen neurologique, tests de d\u00e9ambulations, tests sanguins, tests de dext\u00e9rit\u00e9\u2026<\/p>\n

Par ailleurs, l\u2019efficacit\u00e9 du cannabis th\u00e9rapeutique sur la douleur, mais aussi sur la spasticit\u00e9 et les troubles du sommeil, a \u00e9t\u00e9 \u00e9valu\u00e9e quotidiennement par les patients durant toute la dur\u00e9e de leur traitement.<\/p>\n

Les pr\u00e9parations de cannabis utilis\u00e9es pour ce traitement contenaient 10-25 mg\/ml de THC.<\/p>\n

Comment le CBD et le THC agissent-ils sur la SEP\u00a0?<\/h2>\n

Lors de leur seconde visite, les 28 patients souffrant de scl\u00e9rose en plaques ont eu l\u2019occasion de s\u2019exprimer sur d\u2019\u00e9ventuels effets ind\u00e9sirables li\u00e9s \u00e0 la prise de CBD<\/a> et de THC. Les effets ind\u00e9sirables les plus fr\u00e9quemment rapport\u00e9s \u00e9taient une s\u00e9cheresse au niveau buccal, mais aussi de la somnolence, des \u00e9tourdissements, et des naus\u00e9es allant d\u2019un niveau l\u00e9ger \u00e0 mod\u00e9r\u00e9.<\/p>\n

Dans ce panel, deux sujets ont n\u00e9anmoins pr\u00e9sent\u00e9 des sympt\u00f4mes prononc\u00e9s, \u00e0 savoir des r\u00eaves et une somnolence excessive, ce qui a engendr\u00e9 un arr\u00eat pr\u00e9matur\u00e9 de leur traitement.<\/p>\n

Les doses moyennes de THC et de CBD administr\u00e9es \u00e0 ces patients atteints de scl\u00e9rose en plaque s\u2019\u00e9levaient \u00e0 4 mg et \u00e0 7 mg. Dans la plupart des cas, elles \u00e9taient administr\u00e9es une seule fois par jour, et plut\u00f4t en soir\u00e9e.<\/p>\n

Au terme de cette \u00e9tude, les chercheurs ont pu observer que la douleur avait diminu\u00e9 d\u2019un score NRS m\u00e9dian de 7 \u00e0 4, que le score NRS m\u00e9dian de la spasticit\u00e9 avait lui aussi baiss\u00e9 de 6 \u00e0 2,5, et que celui des troubles du sommeil avait quant \u00e0 lui baiss\u00e9 d\u2019un score NRS m\u00e9dian de 7 \u00e0 3. Aucune alt\u00e9ration de la d\u00e9ambulation, ou de la dext\u00e9rit\u00e9 n\u2019a \u00e9t\u00e9 constat\u00e9e.<\/p>\n

Nous pouvons donc en conclure que le traitement \u00e0 base de THC et de CBD s\u2019est av\u00e9r\u00e9 s\u00fbr, et qu\u2019il a majoritairement \u00e9t\u00e9 bien tol\u00e9r\u00e9 par les patients atteints de scl\u00e9rose en plaques. Il a en effet permis de soulager certains sympt\u00f4mes propres \u00e0 la maladie, tels que des douleurs chroniques intenses, la spasticit\u00e9, ainsi que les troubles du sommeil.<\/p>\n","protected":false},"excerpt":{"rendered":"

Aujourd\u2019hui, l\u2019utilisation m\u00e9dicale du cannabis (CBD et THC) pour lutter contre la douleur chronique et la spasticit\u00e9 chez les personnes souffrant de scl\u00e9rose en plaques (ou SEP) est en augmentation. Toutefois, les preuves attestant de la s\u00e9curit\u00e9 de ce traitement \u00e0 base d\u2019huiles de cannabis m\u00e9dical restent encore limit\u00e9es \u00e0 l\u2019heure actuelle. Soulager les sympt\u00f4mes … <\/p>\n

Lire la suite<\/a><\/p>\n","protected":false},"author":1099,"featured_media":10362,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"generate_page_header":"","mc4wp_mailchimp_campaign":[],"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[214],"tags":[],"class_list":["post-10361","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-effets-et-etudes-du-cbd","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50"],"yoast_head":"\nLutter contre la scl\u00e9rose en plaque avec le CBD et le THC<\/title>\n<meta name=\"description\" content=\"Le CBD et le THC sont aujourd\u2019hui consid\u00e9r\u00e9s comme une piste \u00e9ventuelle pour soulager les sympt\u00f4mes des patients atteints de scl\u00e9rose en plaque.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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